Product Name :
2-Ketobutyric acid (CAS 600-18-0)

Synonym :
alpha-Ketobutyric Acid; Propionylformic acid

Application :
2-Ketobutyric acid is A important member of amino acid metabolism

CAS:
600-18-0

Purity:
≥95%

Molecular Weight:
102.09

Formula :
C4H6O3

Physical state:
Low-Melting Solid

solubility :

Shipping Condition :
Store at -20° C

Melting point:
30-34° C (lit.)

SMILES:
CCC(=O)C(=O)O

References:
:Metabolic and K(ATP) channel-independent actions of keto acid initiators of insulin secretion. | McClenaghan, NH. and Flatt, PR. 2000. Pancreas. 20: 38-46. PMID: 10630382Electrospray ionization mass spectrometry in the structural characterization of some diphenyllead(IV) thiosemicarbazonates. | Casas, JS., et al. 2004. Rapid Commun Mass Spectrom. 18: 1856-64. PMID: 15329880Identification of a sotolon pathway in dry white wines. | Pons, A., et al. 2010. J Agric Food Chem. 58: 7273-9. PMID: 20486709Plasma Metabolic Profiling Analysis of Gout Party on Acute Gout Arthritis Rats Based on UHPLC-Q-TOF/MS Combined with Multivariate Statistical Analysis. | Wang, Y., et al. 2019. Int J Mol Sci. 20: PMID: 31731809Metabolic engineering of Corynebacterium glutamicum WM001 to improve l-isoleucine production. | Zhang, Y., et al. 2021. Biotechnol Appl Biochem. 68: 568-584. PMID: 32474971[Synthesis of L-2-aminobutyric acid by leucine dehydrogenase coupling with an NADH regeneration system]. | Zhang, L., et al. 2020. Sheng Wu Gong Cheng Xue Bao. 36: 992-1001. PMID: 32567282Plasma metabolomic study in perinatally HIV-infected children using 1H NMR spectroscopy reveals perturbed metabolites that sustain during therapy. | Kaur S, U., et al. 2020. PLoS One. 15: e0238316. PMID: 32866201Efficient single whole-cell biotransformation for L-2-aminobutyric acid production through engineering of leucine dehydrogenase combined with expression regulation. | Chen, J., et al. 2021. Bioresour Technol. 326: 124665. PMID: 33540211Metabolic changes from exposure to harmful Maillard reaction products and high-fat diet on Sprague-Dawley rats. | Quan, W., et al. 2021. Food Res Int. 141: 110129. PMID: 33641996Development of efficient microbial cell factory for whole-cell bioconversion of L-threonine to 2-hydroxybutyric acid. | Le, T. and Park, S. 2022. Bioresour Technol. 344: 126090. PMID: 34634464Aroylhydrazone Diorganotin Complexes Causes DNA Damage and Apoptotic Cell Death: From Chemical Synthesis to Biochemical Effects.1279032-69-7 web | Jiang, W.250674-51-2 supplier , et al.PMID:33638630 2021. Int J Mol Sci. 22: PMID: 34948323Effects of Cage and Floor Rearing Systems on the Metabolic Components of the Uropygial Gland in Ducks. | Liu, H., et al. 2022. Animals (Basel). 12: PMID: 35049836Association Among the Gut Microbiome, the Serum Metabolomic Profile and RNA m6A Methylation in Sepsis-Associated Encephalopathy. | Wang, H., et al. 2022. Front Genet. 13: 859727. PMID: 35432460Exercise improves choroid plexus epithelial cells metabolism to prevent glial cell-associated neurodegeneration. | Chen, Y., et al. 2022. Front Pharmacol. 13: 1010785. PMID: 36188600Glucose and non-glucidic nutrients exert permissive effects on 2-keto acid regulation of pancreatic beta-cell function. | McClenaghan, NH. and Flatt, PR. 1999. Biochim Biophys Acta. 1426: 110-8. PMID: 9878701