Product Name :
PMS2 Recombinant Rabbit Monoclonal Antibody [SY08-09]
Predicted band size :
96 kDa
Observed band size :
120 kDa
Synonyms:
DNA mismatch repair gene homologue antibody DNA mismatch repair protein PMS2 antibody H_DJ0042M02.9 antibody HNPCC4 antibody Mismatch repair endonuclease PMS2 antibody Mismatch repair gene PMSL2 antibody PMS 2 antibody PMS1 protein homolog 2 antibody PMS2 antibody PMS2 postmeiotic segregation increased 2 antibody 展开
Function :
This gene is one of the PMS2 gene family members which are found in clusters on chromosome 7. Human PMS2 related genes are located at bands 7p12, 7p13, 7q11, and 7q22. Exons 1 through 5 of these homologues share high degree of identity to human PMS2 .The product of this gene is involved in DNA mismatch repair. The protein forms a heterodimer with MLH1 and this complex interacts with MSH2 bound to mismatched bases. Defects in this gene are associated with hereditary nonpolyposis colorectal cancer, with Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human PMS2 aa 1-50 / 862.
Species reactivity:
Human
Verify application:
WB, IF-Cell, IF-Tissue, IHC-P, IP, FC
Coupling :
unconjugated
Clone number:
SY08-09
RRID:
AB_3069702
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.Perfluoropropionic anhydride Data Sheet Aliquot store at -20℃.2413767-30-1 Price Avoid repeated freeze / thaw cycles.PMID:33487049
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 96 kDa
Positive control :
HeLa, HeLa cell lysate, Jurkat cell lysate, HepG2 cell lysate, U-2 OS cell lysate, human colon carcinoma tissue, human breast carcinoma tissue.