Product Name :
UBE2D2 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
E2(17)KB2 antibody OTTHUMP00000223475 antibody OTTHUMP00000223476 antibody OTTHUMP00000223477 antibody OTTHUMP00000223478 antibody OTTHUMP00000224375 antibody PUBC 1 antibody PUBC1 antibody UB2D2_HUMAN antibody UBC 4 antibody 展开
Function :
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes ‘Lys-48’-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by DDX58/RIG-I in response to viral infection.2-(2-Bromoethyl)-1,3-dioxolane Data Sheet Essential for viral activation of IRF3.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
KLH conjugated synthetic peptide derived from human UBE2D2 31-130/147
Species reactivity:
Human, Mouse, Rat, Chicken, Cow, Horse, Rabbit, Sheep
Verify application:
WB, ELISA
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at -20℃ for one year.4-Bromo-2-chloro-6-fluorobenzaldehyde site Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃.PMID:33651966 When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage buffer solution:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
17 KDa
Positive control :