Product Name :
Thioredoxin Recombinant Rabbit Monoclonal Antibody [JM10-019]
Predicted band size :
12 kDa
Observed band size :
12 kDa
Synonyms:
ADF antibody ATL derived factor antibody ATL-derived factor antibody DKFZp686B1993 antibody MGC61975 antibody SASP antibody Surface associated sulphydryl protein antibody Surface-associated sulphydryl protein antibody testicular tissue protein Li 199 antibody THIO_HUMAN antibody 展开
Function :
Thioredoxin (Trx) is a redox protein that is found in several species, such as bacteria, plants and mammals, and contains a conserved active site, consisting of Trp-Cys-Gly-Pro-Cys. Trx has several biological functions. It acts as a hydrogen donor for ribonucleotide reductase, which is critical for DNA synthesis, and modulates the DNA-binding activity of several transcription factors, including NFkB, AP-1, p53, TFIIIC and glucocorticoid receptor. Trx also stimulates cell growth, is an inhibitor of apoptosis and plays a role in the protection against oxidative stress. Drugs that inhibit Trx have antitumor activity, suggesting that Trx is involved in a variety of human diseases, including cancer. TrxR is a ubiquitously expressed flavoprotein that catalyzes the NADPH-dependent reduction of Trx as well as several other oxidized cellular components.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human Thioredoxin aa 6-50 / 105.Bicyclo[2.2.1]Hept-5-en-2-one custom synthesis
Species reactivity:
Human
Verify application:
WB, IF-Cell, IF-Tissue, IHC-P, IP
Coupling :
unconjugated
Clone number:
JM10-019
RRID:
AB_3070361
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.(2,3-Dihydrobenzofuran-7-yl)boronic acid uses Aliquot store at -20℃ or -80℃.PMID:33499691 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 12 kDa
Positive control :
Hela cell lysates, Hela, MCF-7, SKOV-3, human fallopian tube tissue, human uterus tissue, human small intestine tissue.